Colleen S, Mårdh P A, Schytz A
Scand J Urol Nephrol. 1975;9(3):192-7. doi: 10.3109/00365597509134210.
The concentrations of magnesium and zinc in the seminal fluid of 41 patients with symptoms of non-acute prostatitis and of 11 healthy age-matched males were determined by atomic absorption spectrophotometry. Possible sources of error in the determination of these metals in seminal fluid are discussed. The mean concentration of magnesium in the patients was 56.6 mug/ml (range 19-190) and in the controls 64.5 mug/ml (range 36-165). The corresponding figures for zinc were 79.2 mug/ml (range 13-283) and 67.5 mug/mg (range 34-116). Both in the patients and in the controls there was a significant correlation between the concentration of magnesium and that of zinc. No significant difference was found between the patients and the controls regarding the concentration of magnesium or zinc. From none of the patients could gonococci be cultured. However, in 6 of them, immunofluorescent studies revealed gonococci. The concentration of zinc (48.3 mug/ml) in seminal fluid from these 6 patients was significantly lower than in the remaining 35. Neither in the patients, nor in the controls, was any correlation found between the concentration of magnesium or zinc and that of fructose in seminal fluid. A significant correlation was found between the concentrations of these metals and the antibacterial activity (determined as the inhibitory effect on the growth of Staphylococcus albus) of the seminal fluid from the patients. A negative correlation was found between the concentration of zinc and an increase in the number of white blood cells in expressed prostatic fluid. No correlation was found between magnesium or zinc and the number of spermatozoa or the percentage of abnormal spermatozoa. The findings in the present study suggest that the secretion of magnesium and zinc is decreased in prostatitis. Because of the wide range of variation of magnesium and zinc in seminal fluid of healthy males, determination of these metals is of limited value in the diagnoses of prostatitis in a given case.
采用原子吸收分光光度法测定了41例非急性前列腺炎患者及11例年龄匹配的健康男性精液中的镁和锌浓度。讨论了精液中这些金属测定可能存在的误差来源。患者精液中镁的平均浓度为56.6微克/毫升（范围19 - 190），对照组为64.5微克/毫升（范围36 - 165）。锌的相应数值分别为79.2微克/毫升（范围13 - 283）和67.5微克/毫克（范围34 - 116）。患者组和对照组中，镁浓度与锌浓度之间均存在显著相关性。患者与对照组在镁或锌浓度方面未发现显著差异。所有患者均未培养出淋球菌。然而，其中6例经免疫荧光研究发现有淋球菌。这6例患者精液中的锌浓度（48.3微克/毫升）显著低于其余35例。在患者组和对照组中，均未发现精液中镁或锌浓度与果糖浓度之间存在相关性。发现这些金属的浓度与患者精液的抗菌活性（以对白色葡萄球菌生长的抑制作用来测定）之间存在显著相关性。发现锌浓度与前列腺液中白细胞数量增加呈负相关。未发现镁或锌与精子数量或异常精子百分比之间存在相关性。本研究结果表明，前列腺炎时镁和锌的分泌减少。由于健康男性精液中镁和锌的变化范围较宽，在特定病例中，这些金属的测定对前列腺炎的诊断价值有限。
