Sejeny S A, Eastham R D, Baker S R
J Clin Pathol. 1975 Oct;28(10):812-3. doi: 10.1136/jcp.28.10.812.
Eleven reports of platelet counts were found in the literature which reported a progressive increase, no change, or a progressive fall during pregnancy. The counts had been made using venous or capillary blood, with either simple dilution or red cell lysis prior to enumeration in a haemocytometer, with or without phase-contrast microscopy. It was therefore decided to examine whole blood platelet counts taken during normal pregnancy. Results from 405 venous blood samples, using an electronic platelet counter, confirmed the finding of a significant progressive fall in platelet counts during normal pregnancy, the lowest counts falling in some women outside the recognized normal range of values.
文献中发现了11篇关于血小板计数的报告，这些报告指出孕期血小板计数呈逐渐上升、无变化或逐渐下降。计数采用静脉血或毛细血管血，在血细胞计数器中计数前，使用简单稀释法或红细胞溶解法，有或没有相差显微镜检查。因此，决定检查正常孕期采集的全血血小板计数。使用电子血小板计数器对405份静脉血样本进行检测的结果证实，正常孕期血小板计数显著逐渐下降，部分女性的最低计数低于公认的正常范围值。
