Kwok Henry C K, Morton Randall P, Chaplin John M, McIvor Nicholas P, Sillars Hamish A
Department of Otolaryngology-Head and Neck Surgery, Green Lane Hospital, Auckland, New Zealand.
Laryngoscope. 2002 May;112(5):820-33. doi: 10.1097/00005537-200205000-00010.
The purposes of this study were to examine the quality of life (QL) of patients who received treatment for cancer of the parotid or temporal region, and to identify factors contributing to it. The relationships between clinician-based measures of treatment outcome and the patient-based counterparts were also evaluated.
A retrospective, cross-sectional study was conducted on 23 patients who had received either a temporal bone resection or a combination of parotidectomy and radiotherapy. The QL survey involved both global QL and measures of the appearance, communication, hearing, physical, psychological, and social domains. Patients were assessed clinically for their performance status, facial nerve function, disfigurement, and hearing and the results were compared with patient-rated QL. Correlation between the QL variables and global QL was identified using Spearman correlation tests.
Ongoing physical symptoms, communication difficulties, and social disturbances were associated with poorer global QL (P <.05). No correlation was detected between global QL and objective disfigurement, facial function, and measures of hearing loss. With the exception of hearing testing, clinical assessments generally did not correlate well with patient ratings.
QL measures provide insight into patients' perceptions of the treatment outcome but do not necessarily correlate with the clinicians' views. The use of a global QL measure overcomes the difficulty of extrapolating the impact of symptom scores or observational measures on patients' overall quality of survival.
本研究旨在探讨接受腮腺或颞部癌症治疗患者的生活质量（QL），并确定影响生活质量的因素。同时还评估了基于临床医生的治疗结果测量与基于患者的相应测量之间的关系。
对23例接受颞骨切除术或腮腺切除术加放疗的患者进行了一项回顾性横断面研究。QL调查涉及整体QL以及外观、沟通、听力、身体、心理和社会领域的测量。对患者的表现状态、面神经功能、容貌毁损、听力进行临床评估，并将结果与患者自评的QL进行比较。使用Spearman相关检验确定QL变量与整体QL之间的相关性。
持续的身体症状、沟通困难和社会干扰与较差的整体QL相关（P<.05）。未发现整体QL与客观容貌毁损、面部功能和听力损失测量之间存在相关性。除听力测试外，临床评估一般与患者评分的相关性不佳。
QL测量有助于深入了解患者对治疗结果的看法，但不一定与临床医生的观点相关。使用整体QL测量克服了推断症状评分或观察测量对患者总体生存质量影响的困难。
