Gertner Elie, Hamlar Dave
Department of Otolaryngology/Head and Neck Surgery, University of Minnesota Medical School, St. Paul, USA
J Rheumatol. 2002 Aug;29(8):1795-7.
Cocaine abuse may be associated with a destructive nasal and pharyngeal process felt to be due to ischemia secondary to vasoconstriction. This report is the first to document a necrotizing granulomatous vasculitis associated with nasal destruction and an oronasal fistula in a chronic cocaine user. Cocaine is an environmental insult that may play a role in triggering cerebral and non-cerebral vasculitis including a necrotizing granulomatous vasculitis of the respiratory tract.
可卡因滥用可能与一种破坏性的鼻和咽病变有关，这种病变被认为是由血管收缩继发的缺血所致。本报告首次记录了一名慢性可卡因使用者出现与鼻破坏和口鼻瘘相关的坏死性肉芽肿性血管炎。可卡因是一种环境损害因素，可能在引发包括呼吸道坏死性肉芽肿性血管炎在内的脑和非脑血管炎中起作用。
