Jürgens Gerd, Geldner Niko
ZMBP, Entwicklungsgenetik, Universität Tübingen, Auf der Morgenstelle 3, D-72076 Tübingen, Federal Republic of Germany.
Traffic. 2002 Sep;3(9):605-13. doi: 10.1034/j.1600-0854.2002.30902.x.
Functional analysis of exocytosis in yeast and animal cells has led to the identification of conserved elements and mechanisms of the trafficking machinery over the last decade. Although functional studies of protein secretion in plants are still fairly limited, the Arabidopsis genome sequence provides an opportunity to identify key players of vesicle trafficking that are conserved across the eukaryotic kingdoms. Here, we review and add to recent genome analyses of trafficking components and highlight some plant-specific modifications of the common eukaryotic machinery. Furthermore, we discuss the evidence for targeted, polarised secretion in plant cells, and speculate about possible underlying cargo sorting processes at the trans-Golgi network and endosomes, based on what is known in animals and yeast.
在过去十年中，对酵母和动物细胞胞吐作用的功能分析已促成了运输机制中保守元件和机制的鉴定。尽管植物中蛋白质分泌的功能研究仍然相当有限，但拟南芥基因组序列为鉴定跨真核生物界保守的囊泡运输关键参与者提供了契机。在此，我们回顾并补充了近期对运输组件的基因组分析，并强调了常见真核生物机制中一些植物特有的修饰。此外，我们讨论了植物细胞中靶向、极化分泌的证据，并基于动物和酵母中的已知情况，推测了反式高尔基体网络和内体中可能潜在的货物分选过程。
