Mainardi Elsa, Montanelli Alessandro, Dotti Maria, Nano Rosanna, Moscato Gianna
Department of Clinical Pathology, General Hospital of Crema, Italy.
J Clin Gastroenterol. 2002 Sep;35(3):245-8. doi: 10.1097/00004836-200209000-00009.
An association between celiac disease and other autoimmune disorders--such as insulin-dependent diabetes, Addison's disease, systemic lupus erythematous, rheumatoid arthritis, alopecia areata, and autoimmune endocrine diseases--has been described. The aim of this study was to evaluate the prevalence of celiac disease in 100 patients with autoimmune thyroid disease. Moreover, the monitoring of patients with concomitant celiac and autoimmune thyroid diseases, after a gluten-free diet or a gluten-containing diet, can give important insights into the effect of dietary habits in thyroid autoantibodies modulation. In our study, the prevalence of celiac disease in patients with autoimmune thyroid disease was 2%. In these two celiac patients, the serologic markers became undetectable 6 months after beginning a gluten-free diet. However, thyroid autoantibodies did not positively correlate with dietary habits.
乳糜泻与其他自身免疫性疾病（如胰岛素依赖型糖尿病、艾迪生病、系统性红斑狼疮、类风湿性关节炎、斑秃和自身免疫性内分泌疾病）之间的关联已被描述。本研究的目的是评估100例自身免疫性甲状腺疾病患者中乳糜泻的患病率。此外，对同时患有乳糜泻和自身免疫性甲状腺疾病的患者在采用无麸质饮食或含麸质饮食后进行监测，可深入了解饮食习惯对甲状腺自身抗体调节的影响。在我们的研究中，自身免疫性甲状腺疾病患者中乳糜泻的患病率为2%。在这两名乳糜泻患者中，开始无麸质饮食6个月后，血清学标志物检测不到。然而，甲状腺自身抗体与饮食习惯无正相关。
