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用于放射变色薄膜剂量测定的三种高分辨率数字化仪的比较。

Comparison of three high-resolution digitizers for radiochromic film dosimetry.

作者信息

Gluckman G R, Reinstein L E

机构信息

Department of Radiation Oncology, SUNY at Stony Brook, New York 11794-7028, USA.

出版信息

Med Phys. 2002 Aug;29(8):1839-46. doi: 10.1118/1.1485056.

Abstract

A recently introduced radiographic film scanner from Howtek is evaluated and compared to two other commercially available densitometry systems for its use in radiochromic (RC) film dosimetry in the clinical dose range 0-100 Gy. It has a high-intensity red LED light-source centered at 662 nm (near the major absorption peak for RC film), and is coupled to a CCD linear array detector. This new densitometry system is directly compared to two high-resolution film scanners commonly employed in RC film dosimetry, namely the Lumiscan 75 digitizer (He-Ne laser light source) and the Vidar VXR-16 digitizer (fluorescent light source). A spot densitometer (Nuclear Associates Radiochromic Densitometer) with a filtered 671 nm laser-diode light source is also included as a reference for comparison. The response of the spot densitometer and three high-resolution digitizers is characterized by the dose required to reach a net optical density of 1 (DNOD1), and is 16.0, 37.3, and 46.4 Gy for the Nuclear Associates Radiochromic Densitometer, Howtek MultiRAD 460 and Lumiscan 75 digitizer, respectively. The Vidar VXR-16 does not reach a net optical density of 1. The minimum usable dose at which a 2% level of uncertainty can be achieved (MUD2%) on the three digitizers are 2.6, 6.0, and 38.5 Gy for the Howtek MultiRAD 460, Lumiscan 75, and Vidar VXR-16, respectively. The Howtek MultiRAD 460 shows the greatest sensitivity, lowest MUD2% and best signal-to-noise ratio in the clinical dose range 0-100 Gy. Furthermore, it has no apparent interference (moiré) artifacts that severely limit the low optical density region of the He-Ne laser digitizer. For high-resolution radiochromic dosimetry in the clinical dose range 0-100 Gy, the high-intensity red LED light-source digitizer proves to be the superior modality.

摘要

对Howtek公司最近推出的一款射线照相胶片扫描仪进行了评估,并将其与另外两款市售密度测定系统进行比较,以考察其在临床剂量范围0 - 100 Gy的放射变色(RC)胶片剂量测定中的应用。它有一个以662 nm为中心的高强度红色发光二极管光源(接近RC胶片的主要吸收峰),并与一个电荷耦合器件线性阵列探测器相连。将这种新的密度测定系统直接与RC胶片剂量测定中常用的两款高分辨率胶片扫描仪进行比较,即Lumiscan 75数字化仪(氦氖激光光源)和Vidar VXR - 16数字化仪(荧光光源)。还包括一台带有经过滤的671 nm激光二极管光源的点密度计(Nuclear Associates放射变色密度计)作为比较的参考。点密度计和三款高分辨率数字化仪的响应通过达到净光密度为1所需的剂量(DNOD1)来表征,Nuclear Associates放射变色密度计、Howtek MultiRAD 460和Lumiscan 75数字化仪的DNOD1分别为16.0、37.3和46.4 Gy。Vidar VXR - 16未达到净光密度为1。三款数字化仪上能够实现2%不确定度水平的最小可用剂量(MUD2%),Howtek MultiRAD 460、Lumiscan 75和Vidar VXR - 16分别为2.6、6.0和38.5 Gy。Howtek MultiRAD 460在临床剂量范围0 - 100 Gy内显示出最高的灵敏度、最低的MUD2%和最佳的信噪比。此外,它没有明显的干扰(莫尔)伪影,而这种伪影会严重限制氦氖激光数字化仪的低光密度区域。对于临床剂量范围0 - 100 Gy内的高分辨率放射变色剂量测定,高强度红色发光二极管光源数字化仪被证明是更优越的方式。

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