Ying Bai, Kosoy Michael Y, Maupin Gary O, Tsuchiya Kiyotaka R, Gage Kenneth L
Yunnan Institute of Epidemic Disease Control and Research, Dali City, Yunnan, People's Republic of China.
Am J Trop Med Hyg. 2002 May;66(5):622-7. doi: 10.4269/ajtmh.2002.66.622.
Ecologic and bacteriologic observations of small mammals captured in Yunnan Province in the People's Republic of China indicated that Bartonella infections occurred at a high prevalence among some rodent species. Sequence analyses of the citrate synthase genes of these Bartonella demonstrated that rodents in this region harbored a diverse assemblage of strains. The Bartonella isolates obtained from Apodemus, Eothenomys, and Rattus typically clustered separately by genus of rodent host. Cultures obtained from Rattus rats were genetically related to Bartonella elizabethae, a recognized human pathogen. The finding of Bartonella species in a high proportion of the rodent samples from Yunnan suggests the need to investigate whether these agents might be responsible for cases of febrile illnesses of unknown etiology in southern China and elsewhere in southeastern Asia.
对中华人民共和国云南省捕获的小型哺乳动物进行的生态学和细菌学观察表明，巴尔通体感染在一些啮齿动物物种中具有很高的患病率。对这些巴尔通体的柠檬酸合酶基因进行的序列分析表明，该地区的啮齿动物携带了多种菌株。从姬鼠属、高山姬鼠属和家鼠属分离出的巴尔通体通常按啮齿动物宿主属分别聚类。从家鼠属大鼠获得的培养物在基因上与一种公认的人类病原体伊丽莎白巴尔通体相关。在来自云南的高比例啮齿动物样本中发现巴尔通体物种，这表明有必要调查这些病原体是否可能是中国南方和东南亚其他地区病因不明的发热性疾病病例的病因。
