Bai Ying, Montgomery Susan P, Sheff Kelly W, Chowdhury Manjur A, Breiman Robert F, Kabeya Hidenori, Kosoy Michael Y
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado, USA.
Am J Trop Med Hyg. 2007 Sep;77(3):567-70.
Ecological and bacteriologic observations of small mammals captured in Dhaka, Bangladesh, indicated that Bartonella infections occurred in high prevalence among lesser bandicoot rats (Bandicota bengalensis), black rats (Rattus rattus), and house shrews (Suncus murinus). Sequence analysis of the citrate synthase gene of Bartonella isolates showed that small mammals in Bangladesh harbored a diverse assemblage of strains. Some cultures were genetically related to Bartonella elizabethae, a species identified from a human patient in the United States. Sequences of some other cultures from Bandicota and Rattus rats were identical to sequences of cultures from domestic rats in France, Portugal, and the United States. The finding of Bartonella species in a high proportion of the mammalian samples from Dhaka suggests the need to study whether these agents might be responsible for human cases of febrile illness of unknown etiology in Bangladesh and elsewhere in south Asia.
对在孟加拉国达卡捕获的小型哺乳动物进行的生态学和细菌学观察表明，巴尔通体感染在小斑姬鼠（孟加拉板齿鼠）、黑家鼠（褐家鼠）和家鼩鼱中普遍存在。对巴尔通体分离株的柠檬酸合酶基因进行序列分析表明，孟加拉国的小型哺乳动物携带多种菌株。一些培养物在基因上与伊丽莎白巴尔通体相关，该物种是从美国一名人类患者身上鉴定出来的。来自板齿鼠和褐家鼠的其他一些培养物的序列与法国、葡萄牙和美国家鼠培养物的序列相同。在达卡的大部分哺乳动物样本中发现巴尔通体物种，这表明有必要研究这些病原体是否可能是孟加拉国和南亚其他地区病因不明的发热性疾病人类病例的病因。
