Williams S M, Mitchell E A, Taylor B J
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Box 913, Dunedin, New Zealand.
Arch Dis Child. 2002 Oct;87(4):274-8. doi: 10.1136/adc.87.4.274.
To determine whether the risk factors for SIDS occurring at night were different from those occurring during the day.
Large, nationwide case-control study, with data for 369 cases and 1558 controls in New Zealand.
Two thirds of SIDS deaths occurred at night (between 10 pm and 7 30 am). The odds ratio (95% CI) for prone sleep position was 3.86 (2.67 to 5.59) for deaths occurring at night and 7.25 (4.52 to 11.63) for deaths occurring during the day; the difference was significant. The odds ratio for maternal smoking for deaths occurring at night was 2.28 (1.52 to 3.42) and that for the day 1.27 (0.79 to 2.03); that for the mother being single was 2.69 (1.29 to 3.99) for a night time death and 1.25 (0.76 to 2.04) for a daytime death. Both interactions were significant. The interactions between time of death and bed sharing, not sleeping in a cot or bassinet, Maori ethnicity, late timing of antenatal care, binge drinking, cannabis use, and illness in the baby were also significant, or almost so. All were more strongly associated with SIDS occurring at night.
Prone sleep position was more strongly associated with SIDS occurring during the day, whereas night time deaths were more strongly associated with maternal smoking and measures of social deprivation.
确定婴儿猝死综合征（SIDS）夜间发病的危险因素是否与白天不同。
在新西兰开展的一项大规模全国性病例对照研究，纳入369例病例和1558例对照的数据。
三分之二的SIDS死亡发生在夜间（晚上10点至上午7点30分之间）。夜间死亡时俯卧睡眠姿势的比值比（95%可信区间）为3.86（2.67至5.59），白天死亡时为7.25（4.52至11.63）；差异有统计学意义。夜间死亡时母亲吸烟的比值比为2.28（1.52至3.42），白天为1.27（0.79至2.03）；母亲为单身时，夜间死亡的比值比为2.69（1.29至3.99），白天为1.25（0.76至2.04）。两种交互作用均有统计学意义。死亡时间与同床睡眠、未睡在婴儿床或摇篮、毛利族裔、产前检查时间晚、暴饮、使用大麻以及婴儿患病之间的交互作用也有统计学意义，或几乎有统计学意义。所有这些因素与夜间发生的SIDS关联更强。
俯卧睡眠姿势与白天发生的SIDS关联更强，而夜间死亡与母亲吸烟和社会剥夺指标关联更强。
