Park Hyun-Young, Lee Soo-Ung, Huh Sun, Kong Yoon, Magnaval Jean-François
Department of Parasitology, College of Medicine, Hallym University, Chunchon 200-702, Korea.
Korean J Parasitol. 2002 Sep;40(3):113-7. doi: 10.3347/kjp.2002.40.3.113.
We investigated the sero-prevalence of toxocariasis among healthy Korean adults in 1999. A total of 314 sera from normal inhabitants in Whachon-gun, Gangwondo, Korea was examined for specific antibody levels against excretory-secretory products of second stage larvae of Toxocara (TES). The presence of cross-reactions with other helminthiases such as cysticercosis, paragonimiasis, sparganosis or clonorchiasis was also checked by specific IgG ELISA. Sera showing positive reaction against TES were also tested by IgG immunoblot and by IgE ELISA. Out of 314 subjects, 16 was found to be positive by TES IgG ELISA and immunoblot, among whom 12 were also positive by TES IgE ELISA. Among the 16 seropositive samples, two sera showed positive reaction against Paragonimus and sparganum antigen, respectively. These results inferred that cross-reactions were negligible between toxocariasis and other helminthiases. Toxocariasis seroprevalence among Korean rural adults was detected to be approximately 5%.
1999年，我们调查了韩国健康成年人中弓蛔虫病的血清流行率。对韩国江原道华川郡314名正常居民的血清进行检测，以确定其针对弓蛔虫第二期幼虫排泄分泌产物（TES）的特异性抗体水平。还通过特异性IgG ELISA检测了与其他蠕虫病（如囊尾蚴病、肺吸虫病、裂头蚴病或华支睾吸虫病）的交叉反应。对TES呈阳性反应的血清也通过IgG免疫印迹法和IgE ELISA进行检测。在314名受试者中，16人经TES IgG ELISA和免疫印迹法检测呈阳性，其中12人经TES IgE ELISA检测也呈阳性。在这16份血清阳性样本中，两份血清分别对肺吸虫和裂头蚴抗原呈阳性反应。这些结果表明，弓蛔虫病与其他蠕虫病之间的交叉反应可忽略不计。韩国农村成年人中弓蛔虫病的血清流行率约为5%。
