Clayton D A, Doda J N, Friedberg E C
Basic Life Sci. 1975;5B:589-91. doi: 10.1007/978-1-4684-2898-8_26.
We have assayed the ability of mammalian cells to remove pyrimidine dimers from their mitochondrial DNA. The results indicate that pyrimidine dimers are not repaired for as long as 48 hr after UV irradiation. Furthermore, molecules containing pyrimidine dimers are unable to replicate and are simply diluted out in subsequent cell divisions.
我们检测了哺乳动物细胞从其线粒体DNA中去除嘧啶二聚体的能力。结果表明，紫外线照射后长达48小时内，嘧啶二聚体都未得到修复。此外，含有嘧啶二聚体的分子无法复制，只是在随后的细胞分裂中被稀释掉。
