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山羊对表达小反刍兽疫血凝素蛋白的羊痘疫苗的免疫反应。

Goat immune response to capripox vaccine expressing the hemagglutinin protein of peste des petits ruminants.

作者信息

Diallo A, Minet C, Berhe G, Le Goff C, Black D N, Fleming M, Barrett T, Grillet C, Libeau G

机构信息

Cirad, Programme Santé Animale, Campus International de Baillarguet, 34398 Montpellier Cedex 05, France.

出版信息

Ann N Y Acad Sci. 2002 Oct;969:88-91. doi: 10.1111/j.1749-6632.2002.tb04356.x.

Abstract

Sheep-pox and capripox are contagious diseases of domestic small ruminants for which the causal agent is a poxvirus classified into the Capripoxvirus genus. Viruses of this group have a host range specific to sheep, goats, cattle, and possibly buffalo. Thus, they are clearly indicated as vectors for the development of recombinant vaccines for peste des petits ruminants (PPR). Here we report the immune response of goats inoculated with a recombinant capripox-PPR hemagglutinin.

摘要

绵羊痘和山羊痘是家养小反刍动物的传染性疾病,其病原体是一种归类于山羊痘病毒属的痘病毒。该病毒组的病毒具有特定于绵羊、山羊、牛以及可能还有水牛的宿主范围。因此,它们被明确视为开发小反刍兽疫(PPR)重组疫苗的载体。在此,我们报告接种重组山羊痘 - PPR血凝素的山羊的免疫反应。

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