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落花生水提取物对正常及四氧嘧啶诱导的糖尿病大鼠的降血糖和降血脂作用

Hypoglycemic and hypolipidemic effects of aqueous extract of Arachis hypogaea in normal and alloxan-induced diabetic rats.

作者信息

Bilbis L S, Shehu R A, Abubakar M G

机构信息

Biochemistry Department, Usmanu Danfodiyo University, Sokoto, Nigeria.

出版信息

Phytomedicine. 2002 Sep;9(6):553-5. doi: 10.1078/09447110260573191.

DOI:10.1078/09447110260573191
PMID:12403165
Abstract

The hypoglycemic and hypolipidemic effect of aqueous extract of Arachis hypogaea was investigated in normal and alloxan-induced diabetic rats. The extract caused a significant (P < 0.05) decrease of fasting blood glucose of both normal and alloxan-induced diabetic rats from 102.60 +/- 1.65 mg/dl to 88.79 +/- 0.94 mg/dl for normal and 189.0 +/- 30.79 mg/dl to 107.55 +/- 1.54 mg/dl for alloxan-induced diabetic rats. The extract also caused a significant (P < 0.05) decrease in serum triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol in both normal and alloxan-induced diabetic rats.

摘要

研究了落花生水提取物对正常大鼠和四氧嘧啶诱导的糖尿病大鼠的降血糖和降血脂作用。该提取物使正常大鼠和四氧嘧啶诱导的糖尿病大鼠的空腹血糖均显著降低(P < 0.05),正常大鼠从102.60±1.65毫克/分升降至88.79±0.94毫克/分升,四氧嘧啶诱导的糖尿病大鼠从189.0±30.79毫克/分升降至107.55±1.54毫克/分升。该提取物还使正常大鼠和四氧嘧啶诱导的糖尿病大鼠的血清甘油三酯、总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇均显著降低(P < 0.05)。

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