Hernández-Alonso Pablo, Camacho-Barcia Lucía, Bulló Mònica, Salas-Salvadó Jordi
Human Nutrition Unit, Biochemistry and Biotechnology Department, Faculty of Medicine and Health Sciences, University Hospital of Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, St/Sant Llorenç 21, 43201 Reus, Spain.
CIBERobn Physiopathology of Obesity and Nutrition, Instituto de Salud Carlos III, 28029 Madrid, Spain.
Nutrients. 2017 Jun 28;9(7):673. doi: 10.3390/nu9070673.
Nuts and dried fruit are essential foods in the Mediterranean diet. Their frequent consumption has been associated with the prevention and/or the management of such metabolic conditions as type 2 diabetes (T2D), metabolic syndrome and cardiovascular diseases. Several previous reviews of epidemiological studies and clinical trials have evaluated the associations of nuts and/or dried fruit with various metabolic disorders. However, no reviews have focused on the mechanisms underlying the role of nuts and/or dried fruit in insulin resistance and T2D. This review aims to report nut and dried-fruit nutritional interventions in animals and humans, and to focus on mechanisms that could play a significant role in the prevention and treatment of insulin resistance and T2D.
坚果和干果是地中海饮食中的重要食物。经常食用它们与预防和/或管理2型糖尿病（T2D）、代谢综合征和心血管疾病等代谢状况有关。此前有几项关于流行病学研究和临床试验的综述评估了坚果和/或干果与各种代谢紊乱之间的关联。然而，尚无综述关注坚果和/或干果在胰岛素抵抗和T2D中作用的潜在机制。本综述旨在报告对动物和人类进行的坚果和干果营养干预，并关注可能在预防和治疗胰岛素抵抗及T2D中发挥重要作用的机制。
