Mortz Charlotte Gotthard, Lauritsen Jens Martin, Bindslev-Jensen Carsten, Andersen Klaus Ejner
Department of Dermatology, Odense University Hospital, Denmark.
Acta Derm Venereol. 2002;82(5):352-8. doi: 10.1080/000155502320624087.
The aims of this cross-sectional study were to establish the prevalence measures of contact allergy and allergic contact dermatitis in 8th grade schoolchildren (aged 12-16 years) in Odense, Denmark, and to examine the associations with atopic dermatitis, inhalant allergy and hand eczema. Contact allergy to a standard series allergen was found in 15.2% of schoolchildren. The point prevalence of allergic contact dermatitis was 0.7% and the lifetime prevalence 7.2%, predominantly in girls. The most common contact allergens were nickel (8.6%) and fragrance mix (1.8%). Nickel allergy was clinically relevant in 69% and fragrance allergy in 29% of cases. A significant association was found between contact allergy and hand eczema while no association was found between contact allergy and atopic dermatitis or inhalant allergy. In the future this cohort of schoolchildren will be followed with regard to the course and development of atopic diseases, hand eczema and contact dermatitis. Key words: school-
这项横断面研究的目的是确定丹麦欧登塞市8年级学童（年龄在12至16岁之间）接触性过敏和过敏性接触性皮炎的患病率，并研究其与特应性皮炎、吸入性过敏和手部湿疹的关联。在15.2%的学童中发现对标准系列变应原的接触性过敏。过敏性接触性皮炎的现患率为0.7%，终生患病率为7.2%，主要见于女孩。最常见的接触性变应原是镍（8.6%）和香料混合物（1.8%）。在69%的镍过敏病例和29%的香料过敏病例中，镍过敏和香料过敏具有临床相关性。接触性过敏与手部湿疹之间存在显著关联，而接触性过敏与特应性皮炎或吸入性过敏之间未发现关联。未来，将对这一队列的学童随访其特应性疾病、手部湿疹和接触性皮炎的病程及发展情况。关键词：学校-
