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西班牙巴塞罗那一家大学医院在3年时间里产抑制剂耐药β-内酰胺酶大肠埃希菌临床分离株的流行情况。

Prevalence of clinical isolates of Escherichia coli producing inhibitor-resistant beta-lactamases at a University Hospital in Barcelona, Spain, over a 3-year period.

作者信息

Miró Elisenda, Navarro Ferran, Mirelis Beatriz, Sabaté Montserrat, Rivera Alba, Coll Pere, Prats Guillem

机构信息

Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma 08025 Barcelona, Spain.

出版信息

Antimicrob Agents Chemother. 2002 Dec;46(12):3991-4. doi: 10.1128/AAC.46.12.3991-3994.2002.

DOI:10.1128/AAC.46.12.3991-3994.2002
PMID:12435708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC132771/
Abstract

About 7% of 7,252 nonduplicated clinical Escherichia coli strains from a Spanish hospital showed reduced susceptibility to amoxicillin-clavulanate. Of these, 0.37% produced the IRTs TEM-30, TEM-31, TEM-33, TEM-34, TEM-37, TEM-40, TEM-51, and TEM-54; 5.3% were probable class C beta-lactamase overproducers; 0.8% were probable TEM-1 hyperproducers; 0.18% produced OXA-30; 0.15% overexpressed SHV-1; and 0.03% produced a PSE-1 enzyme.

摘要

来自一家西班牙医院的7252株非重复临床大肠杆菌菌株中，约7%对阿莫西林-克拉维酸的敏感性降低。其中，0.37%产生IRT TEM-30、TEM-31、TEM-33、TEM-34、TEM-37、TEM-40、TEM-51和TEM-54；5.3%可能是C类β-内酰胺酶过量产生菌；0.8%可能是TEM-1过量产生菌；0.18%产生OXA-30；0.15%过表达SHV-1；0.03%产生PSE-1酶。

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