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QUANTITATIVE GENETIC MODELS FOR DEVELOPMENT, EPIGENETIC SELECTION, AND PHENOTYPIC EVOLUTION.发育、表观遗传选择和表型进化的定量遗传模型
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Genome-wide epistatic interaction analysis reveals complex genetic determinants of circadian behavior in mice.全基因组上位性相互作用分析揭示了小鼠昼夜节律行为的复杂遗传决定因素。
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Developmental interactions and the constituents of quantitative variation.发育相互作用与数量变异的组成部分
Evolution. 2001 Feb;55(2):232-45. doi: 10.1111/j.0014-3820.2001.tb01289.x.
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Modeling genetic architecture: a multilinear theory of gene interaction.遗传结构建模:基因相互作用的多线性理论
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Competition among body parts in the development and evolution of insect morphology.昆虫形态发育与进化过程中身体各部分之间的竞争。
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一种关于发育相互作用进化的群体遗传学通用理论。

A general population genetic theory for the evolution of developmental interactions.

作者信息

Rice Sean H

机构信息

Department of Ecology and Evolutionary Biology, Osborn Memorial Laboratories, Yale University, New Haven, CT 06520, USA.

出版信息

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15518-23. doi: 10.1073/pnas.202620999. Epub 2002 Nov 18.

DOI:10.1073/pnas.202620999
PMID:12438697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC137749/
Abstract

The development of most phenotypic traits involves complex interactions between many underlying factors, both genetic and environmental. To study the evolution of such processes, a set of mathematical relationships is derived that describe how selection acts to change the distribution of genetic variation given arbitrarily complex developmental interactions and any distribution of genetic and environmental variation. The result is illustrated by using it to derive models for the evolution of dominance and for the evolutionary consequences of asymmetry in the distribution of genetic variation.

摘要

大多数表型性状的发育涉及许多潜在因素(包括遗传因素和环境因素)之间的复杂相互作用。为了研究此类过程的进化,我们推导了一组数学关系,这些关系描述了在任意复杂的发育相互作用以及遗传和环境变异的任何分布情况下,选择如何作用以改变遗传变异的分布。通过将其用于推导显性进化模型以及遗传变异分布不对称的进化后果模型来说明这一结果。