萨卡辛G，一种新型抗李斯特菌细菌素。
Sakacin g, a new type of antilisterial bacteriocin.
作者信息
Simon L, Fremaux C, Cenatiempo Y, Berjeaud J M
机构信息
Laboratoire de Microbiologie Fondamentale et Appliquée, EA 2224, IBMIG, 86022 Poitiers, France.
出版信息
Appl Environ Microbiol. 2002 Dec;68(12):6416-20. doi: 10.1128/AEM.68.12.6416-6420.2002.
Abstract
Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2. Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity.
摘要
萨卡辛G是一种由清酒乳杆菌2512产生的、含有37个氨基酸残基的IIa类细菌素，由重复的结构基因skgA1和skgA2编码。萨卡辛G似乎很独特，就其抗菌活性所需的双二硫键而言，它似乎是类片球菌素样细菌素与肠膜菌素样细菌素之间的一种中间产物，在序列同源性、抑制谱和比活性方面也是如此。
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