Smith G A, Gussen R
Arch Otolaryngol. 1976 Feb;102(2):108-11. doi: 10.1001/archotol.1976.00780070086013.
Temporal bone studies in an adult with a moderately severe, bilateral sensorineural hearing loss revealed bilateral cochlear changes 13 years after mumps infection. The organ of Corti was completely absent in the greater part of the superior horizontal basal limbs, with occasional hair cell loss throughout the rest of the cochlea. The outer sulcus cell area was degenerated. The stria vascularis was normal, as was the tectorial membrane, except for small hyaline droplets. The number of nerve fibers was extremely decreased in the spiral bony lamina of the basal turns. Basophilic material, possibily representing degeneration of otoliths, was present in the saccule and utricle, bilaterally, with small amounts in all of the ampullae. This was considered to be either a possible result of cytotoxic cancerocidal therapy, or an incidental nonspecific change.
对一名患有中度重度双侧感音神经性听力损失的成年人进行的颞骨研究显示，在腮腺炎感染13年后出现双侧耳蜗改变。上水平基底肢大部分区域的柯蒂器完全缺失，耳蜗其余部分偶尔有毛细胞丢失。外沟细胞区域退化。血管纹正常，除了有小的透明滴外，盖膜也正常。基底转螺旋骨板中的神经纤维数量极度减少。双侧球囊和椭圆囊中存在嗜碱性物质，可能代表耳石退化，所有壶腹中也有少量。这被认为要么是细胞毒性抗癌治疗的可能结果，要么是偶然的非特异性改变。
