Aijö Marja, Heikkinen Elno, Schroll Marianne, Steen Bertil
Finnish Centre for Interdisciplinary Gerontology, University of Jyväskylä.
Aging Clin Exp Res. 2002 Jun;14(3 Suppl):83-9.
The purpose of this 5-year follow-up study was to investigate the relationship between physical activity and mortality in persons aged 75 in three Nordic localities. The study is part of the common NOrdic Research project on Ageing (NORA). The samples consisted of 221 men and 259 women in Glostrup, Denmark, 159 men and 209 women in Göteborg, Sweden, and 119 men and 236 women in Jyväskylä, Finland. Physical activity was measured with a self-report questionnaire, from which a dichotomous explanatory variable was created for the subsequent analysis. Covariates examined in this study were smoking, use of alcohol and the presence of cardiovascular diseases. Baseline measurements were conducted in Glostrup and Jyväskylä in 1989, and a year later in Göteborg. Mortality data was collected from the mortality registry in each country. The follow-up period was 5 years. Fisher's exact test, Cox regression and Kaplan-Meier survival analysis were used in the statistical analysis of the data. The results showed that when physical activity alone was considered, inactivity was associated with an increased mortality risk in all groups except for the men in Jyväskylä. Of the covariates, only smoking and cardiovascular diseases were found to be associated with increased mortality risk and only among the women in Göteborg and Jyväskylä, respectively. When the effect of physical activity on mortality was analyzed together with the covariates, the relationship between physical inactivity and increased mortality risk remained significant in all groups except for the men in Jyväskylä. In addition to this, smoking remained a significant predictor of mortality for women in Göteborg, and the effect of cardiovascular diseases for women in Jyväskylä was nearly significant. The results showed that being physically active predicted survival for persons aged 75 during the follow-up period in all three localities.
这项为期5年的随访研究旨在调查北欧三个地区75岁人群的身体活动与死亡率之间的关系。该研究是北欧老龄化共同研究项目（NORA）的一部分。样本包括丹麦格罗斯楚普的221名男性和259名女性、瑞典哥德堡的159名男性和209名女性，以及芬兰于韦斯屈莱的119名男性和236名女性。通过一份自我报告问卷来测量身体活动情况，并据此创建一个二分的解释变量用于后续分析。本研究中考察的协变量包括吸烟、饮酒情况以及心血管疾病的存在情况。1989年在格罗斯楚普和于韦斯屈莱进行了基线测量，一年后在哥德堡进行了测量。死亡率数据从每个国家的死亡登记处收集。随访期为5年。在对数据进行统计分析时使用了费舍尔精确检验、Cox回归和Kaplan-Meier生存分析。结果表明，仅考虑身体活动时，除了于韦斯屈莱的男性外，所有组中不活动都与死亡率风险增加有关。在协变量中，仅发现吸烟和心血管疾病分别与哥德堡和于韦斯屈莱的女性死亡率风险增加有关。当将身体活动对死亡率的影响与协变量一起分析时，除了于韦斯屈莱的男性外，所有组中身体不活动与死亡率风险增加之间的关系仍然显著。除此之外，吸烟仍然是哥德堡女性死亡率的一个显著预测因素，心血管疾病对于韦斯屈莱女性的影响几乎显著。结果表明，身体活跃可预测所有三个地区75岁人群在随访期间的生存情况。
