Sanjuás Carlos, Alonso Jordi, Prieto Luis, Ferrer Montse, Broquetas Joan M, Antó Josep M
Department of Pneumology, Hospital del Mar, Barcelona, Spain.
Qual Life Res. 2002 Dec;11(8):729-38. doi: 10.1023/a:1020897816228.
The aim of the study is to compare the performance of the Juniper Asthma Quality of Life Questionnaire (AQLQ) and the St George's Respiratory Questionnaire (SGRQ) in a sample of asthmatic patients, representative of a broad spectrum of asthma severity. We studied 116 patients with a mean age (SD) of 42.6 (18.3) year. Patients were assessed twice, at recruitment and after 2 months, to determine the reliability, validity and responsiveness of the AQLQ and the SGRQ. Both questionnaires showed good reliability coefficients (> or = 0.70) which reached the standards for comparison at individual level (> or = 0.90) in the case of activity, impacts and overall SGRQ scores as well as symptoms, activities and overall AQLQ scores. Both AQLQ and SGRQ were able to discriminate among groups of patients based on asthma severity and control and showed, except for the symptoms domain of the SGRQ, large (standardized response means >0.8) and significant changes in the group of patients that improved at follow-up. We conclude that the AQLQ and SGRQ have shown high reliability and validity and, with the exception of the SGRQ symptoms, a high level of responsiveness. In overall terms, not one of these instruments seems to behave better than the other.
本研究旨在比较杜松哮喘生活质量问卷（AQLQ）和圣乔治呼吸问卷（SGRQ）在一组具有广泛哮喘严重程度代表性的哮喘患者样本中的表现。我们研究了116例患者，平均年龄（标准差）为42.6（18.3）岁。在招募时和2个月后对患者进行了两次评估，以确定AQLQ和SGRQ的信度、效度和反应度。两份问卷均显示出良好的信度系数（≥0.70），在活动、影响和SGRQ总分以及症状、活动和AQLQ总分方面，达到了个体水平比较的标准（≥0.90）。AQLQ和SGRQ均能够根据哮喘严重程度和控制情况区分患者组，并且除SGRQ的症状领域外，在随访中病情改善的患者组显示出较大（标准化反应均值>0.8）且显著的变化。我们得出结论，AQLQ和SGRQ已显示出高信度和效度，并且除SGRQ症状外，反应度较高。总体而言，这些工具中似乎没有一个比另一个表现更好。
