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拟暗果蝇酯酶-5位点二聚化能力的多态性。

Polymorphism for dimerizing ability at the esterase-5 locus in Drosophila pseudoobscura.

作者信息

Cobbs G

出版信息

Genetics. 1976 Jan;82(1):53-62. doi: 10.1093/genetics/82.1.53.

Abstract

Three new alleles are reported at the esterase-5 locus of Drosophila pseudoobscura. All three of these alleles are different from those previously reported in their ability to dimerize. One allele will not form heterodimers or homodimers and exists only as a monomer. A second allele does form heterodimers but will not form homodimers. The third allele forms both hetero- and homodimers as well as forming monomers. Estimates of the frequency of these alleles in a natural population are given. The existence of these is discussed with respect to recently proposed models for a molecular mechanism for heterosis.

摘要

本文报道了果蝇酯酶-5基因座上的三个新等位基因。这三个等位基因在二聚化能力方面均与先前报道的不同。其中一个等位基因既不形成异源二聚体也不形成同源二聚体,仅以单体形式存在。第二个等位基因能形成异源二聚体,但不能形成同源二聚体。第三个等位基因既能形成异源二聚体和同源二聚体,也能形成单体。文中给出了这些等位基因在自然种群中的频率估计。并结合最近提出的杂种优势分子机制模型对其存在情况进行了讨论。

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本文引用的文献

1
Purification of esterase-5 from Drosophila pseudoobscura.从拟暗果蝇中纯化酯酶-5
Biochim Biophys Acta. 1966 Aug 10;122(2):281-8. doi: 10.1016/0926-6593(66)90068-3.

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