Cobbs G
Genetics. 1976 Jan;82(1):53-62. doi: 10.1093/genetics/82.1.53.
Three new alleles are reported at the esterase-5 locus of Drosophila pseudoobscura. All three of these alleles are different from those previously reported in their ability to dimerize. One allele will not form heterodimers or homodimers and exists only as a monomer. A second allele does form heterodimers but will not form homodimers. The third allele forms both hetero- and homodimers as well as forming monomers. Estimates of the frequency of these alleles in a natural population are given. The existence of these is discussed with respect to recently proposed models for a molecular mechanism for heterosis.
本文报道了果蝇酯酶-5基因座上的三个新等位基因。这三个等位基因在二聚化能力方面均与先前报道的不同。其中一个等位基因既不形成异源二聚体也不形成同源二聚体，仅以单体形式存在。第二个等位基因能形成异源二聚体，但不能形成同源二聚体。第三个等位基因既能形成异源二聚体和同源二聚体，也能形成单体。文中给出了这些等位基因在自然种群中的频率估计。并结合最近提出的杂种优势分子机制模型对其存在情况进行了讨论。
