Hakim Euis Holisotan, Aimi Norio, Kitajima Mariko, Takayama Hiromitsu
Department of Chemistry, Institut Teknologi Bandung, Jalan Ganeca 10, Bandung 40132, Indonesia.
Fitoterapia. 2002 Dec;73(7-8):668-73. doi: 10.1016/s0367-326x(02)00226-5.
A new prenylated flavone, named artoindonesianin P (1), was isolated from the tree bark of Artocarpus lanceifolius, together with three known related compounds, artobiloxanthone (2), cycloartobiloxanthone (3) and artonol B (4). The structure of artoindonesianin P 1 was determined on the basis of spectral evidence (MS, 1H and 13C NMR) and by comparison with known related compounds. Compounds 1-4 exhibited significant cytotoxicity against murine P388 leukemia cells.
从兰叶波罗蜜的树皮中分离出一种新的异戊烯基黄酮,命名为波罗蜜宁P(1),同时还分离出三种已知的相关化合物,即波罗蜜黄烷酮(2)、环波罗蜜黄烷酮(3)和波罗蜜醇B(4)。通过光谱数据(质谱、1H和13C核磁共振)并与已知相关化合物进行比较,确定了波罗蜜宁P(1)的结构。化合物1 - 4对小鼠P388白血病细胞表现出显著的细胞毒性。