Tipples Graham A, Stephens Gwen M, Sherlock Chris, Bowler Margrit, Hoy Benny, Cook Darrel, Grose Charles
National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
Emerg Infect Dis. 2002 Dec;8(12):1504-5. doi: 10.3201/eid0812.020118.
In 1998, a varicella-zoster virus glycoprotein E (gE) mutant virus (VZV-MSP) was isolated from a child with chickenpox. VZV-MSP, representing a second VZV serotype, was considered a rarity. We isolated another VZV-MSP-like virus from an elderly man with herpes zoster. These gE mutant viruses may have arisen through independent mutation or may represent a distinct VZV subpopulation that emerged more than 50 years ago.
1998年,从一名患水痘的儿童体内分离出一种水痘-带状疱疹病毒糖蛋白E(gE)突变病毒(VZV-MSP)。VZV-MSP代表第二种水痘-带状疱疹病毒血清型,被认为很罕见。我们从一名患带状疱疹的老年男性体内分离出另一种类似VZV-MSP的病毒。这些gE突变病毒可能是通过独立突变产生的,也可能代表一个50多年前出现的独特的水痘-带状疱疹病毒亚群。