携带编码金属β-内酰胺酶VIM-1的自我转移性多耐药质粒的大肠杆菌。
Escherichia coli with a self-transferable, multiresistant plasmid coding for metallo-beta-lactamase VIM-1.
作者信息
Miriagou Vivi, Tzelepi Eva, Gianneli Dimitra, Tzouvelekis Leonidas S
机构信息
Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
出版信息
Antimicrob Agents Chemother. 2003 Jan;47(1):395-7. doi: 10.1128/AAC.47.1.395-397.2003.
Abstract
An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-beta-lactamase VIM-1. bla(VIM-1), along with aacA7, dhfrI, and aadA, was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC-derived gene, not associated with the integron, was also located in the same plasmid.
摘要
从希腊一名住院患者身上分离出一株对碳青霉烯类药物敏感性降低的大肠杆菌菌株。该菌株携带一个编码金属β-内酰胺酶VIM-1的可自我转移质粒。bla(VIM-1)与aacA7、dhfrI和aadA一起作为一个基因盒包含在一个新型1类整合子中。一个与整合子无关的弗氏柠檬酸杆菌ampC衍生基因也位于同一质粒上。
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