Sánchez-Fauquier A, Roman E, Colomina J, Wilhelmi I, Glass R I, Jiang B
Viral Gastroenteritis Section, Instituto de Salud Carlos III, Centro Nacional de Microbiología, Madrid, Spain.
Arch Virol. 2003 Feb;148(2):399-404. doi: 10.1007/s00705-002-0921-4.
Group C rotavirus causes sporadic cases and outbreaks of acute diarrhea in children and adults in many countries, but has never been detected among children in Spain. In a recently conducted surveillance study to screen fecal specimens for bacteria and viruses from a cohort of 822 young children who were treated for acute diarrhea in Madrid, no pathogens were detected in fecal specimens from 238 (29%) children. In this study, we examined 147 of those specimens for group C rotavirus by EIA and PCR and found 22 (15%) were positive. Our findings demonstrate that group C rotavirus is an important cause of childhood diarrhea in Spain.
C组轮状病毒在许多国家导致儿童和成人散发性病例及急性腹泻暴发,但在西班牙儿童中从未被检测到。在最近一项对马德里822名因急性腹泻接受治疗的幼儿队列的粪便标本进行细菌和病毒筛查的监测研究中,238名(29%)儿童的粪便标本未检测到病原体。在本研究中,我们通过酶免疫分析(EIA)和聚合酶链反应(PCR)对其中147份标本进行了C组轮状病毒检测,发现22份(15%)呈阳性。我们的研究结果表明,C组轮状病毒是西班牙儿童腹泻的一个重要病因。