Morrow R H, Kisuule A, Pike M C, Smith P G
J Natl Cancer Inst. 1976 Mar;56(3):479-83. doi: 10.1093/jnci/56.3.479.
An epidemiologic study of 123 patients residing in the Mengo Districts of Uganda, with onset of symptoms of diagnosed Burkitt's lymphoma (BL) in the period 1959-68, revealed a substantial decline in incidence of BL during that decade. Other significant findings included differences by ethnic group in age of patient at onset of BL, a change in the proportions of patients by ethnic group over the decade, a lower incidence rate of BL in the countries of higher altitude, and a seasonal pattern of onset. There was no evidence of the time space clustering previously reported for BL in Uganda. The changing pattern of BL in the Mengo Districts was consistent with the hypothesis that severe malaria infection not only is important in the development of BL but also precipitates onset.
一项针对居住在乌干达蒙戈区的123名患者的流行病学研究发现，在1959年至1968年期间，被诊断出患有伯基特淋巴瘤（BL）且出现症状的患者中，该十年间BL的发病率大幅下降。其他重要发现包括：不同种族群体在BL发病时患者的年龄存在差异；十年间不同种族群体患者的比例发生了变化；海拔较高国家的BL发病率较低；以及发病的季节性模式。没有证据表明此前报道的乌干达BL存在时空聚集现象。蒙戈区BL模式的变化与以下假设一致，即严重的疟疾感染不仅在BL的发展中起重要作用，而且会促使发病。
