Whitford David L, Griffin Simon J, Prevost A Toby
Department of Public Health and Primary Care, University of Cambridge.
Br J Gen Pract. 2003 Jan;53(486):9-14.
The prevalence of type 2 diabetes is known to vary between countries, districts and general practices. The influence of early detection and screening on the variation of prevalence between general practices has not previously been investigated.
To test the hypothesis that the prevalence of type 2 diabetes is associated with awareness of and screening for diabetes within general practices and to explore other factors that may explain the variation in prevalence between practices.
Cross-sectional study of general practices.
Forty-two general practices in Newcastle and North Tyneside; 20% random sample of patients with type 2 diabetes (n = 1056).
Factors thought to be associated with the variation of type 2 diabetes prevalence were collected from general practices through practice managers, medical records, and patient questionnaire. Pearson's correlation coefficient was used to quantify the association, and variables significant at the 5% level were entered into a multiple linear regression model.
There was a wide inter-practice variation in age/sex standardised type 2 diabetes prevalence (range = 0.69% to 2.73%; P < 0.001). There was no significant association between the prevalence of type 2 diabetes and the proportion of patients detected outside primary care or the proportion of patients detected through screening, accounting for only 2% and 3% of the variation in type 2 prevalence between practices, respectively. The mean Townsend deprivation score accounted for 42% of the variation in type 2 diabetes prevalence between practices, with more deprived practices having a higher prevalence.
This study suggests that socieconomic deprivation, rather than detection through screening or awareness of diabetes, accounts for much of the variation in prevalence of type 2 diabetes between practices.
已知2型糖尿病的患病率在不同国家、地区和普通医疗实践之间存在差异。早期检测和筛查对普通医疗实践之间患病率差异的影响此前尚未得到研究。
检验2型糖尿病患病率与普通医疗实践中对糖尿病的认知和筛查相关的假设,并探索其他可能解释不同医疗实践之间患病率差异的因素。
普通医疗实践的横断面研究。
纽卡斯尔和北泰恩赛德的42家普通医疗诊所;2型糖尿病患者的20%随机样本(n = 1056)。
通过诊所管理人员、病历和患者问卷从普通医疗诊所收集被认为与2型糖尿病患病率差异相关的因素。使用Pearson相关系数来量化这种关联,并将在5%水平上显著的变量纳入多元线性回归模型。
年龄/性别标准化的2型糖尿病患病率在不同医疗实践之间存在很大差异(范围 = 0.69%至2.73%;P < 0.001)。2型糖尿病患病率与在初级医疗之外检测出的患者比例或通过筛查检测出的患者比例之间没有显著关联,分别仅占不同医疗实践中2型患病率差异的2%和3%。平均汤森德剥夺分数占不同医疗实践中2型糖尿病患病率差异的42%,贫困程度越高的医疗实践患病率越高。
这项研究表明,社会经济剥夺而非通过筛查检测或对糖尿病的认知,是不同医疗实践之间2型糖尿病患病率差异的主要原因。