Lee Sanghyun, Shin Dong-Sun, Oh Ki-Bong, Shin Kuk Hyun
Natural Products Research Institute and College of Pharmacy, Seoul National University, Seoul 110-460, Korea.
Arch Pharm Res. 2003 Jan;26(1):40-2. doi: 10.1007/BF03179929.
Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate antibacterial activities against G (+) and G (-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 microg/ml.
从刺五加叶中分离得到齐墩果酸（1）、金丝桃苷（2）和齐墩果苷（3），并对它们对6种细菌菌株的抑制活性进行了测试。其中，齐墩果酸（1）对革兰氏阳性菌和革兰氏阴性菌显示出广泛但中等程度的抗菌活性，最低抑菌浓度（MIC）在50 - 100微克/毫升范围内。
