年龄相关性眼病研究（AREDS）中的国立眼科研究所视觉功能问卷：AREDS报告第10号。
National Eye Institute Visual Function Questionnaire in the Age-Related Eye Disease Study (AREDS): AREDS Report No. 10.
作者信息
Clemons Traci E, Chew Emily Y, Bressler Susan B, McBee Wendy
机构信息
AREDS Coordinating Center, The EMMES Corporation, 401 N Washington Street, Suite 700, Rockville, MD 20850-1707, USA.
出版信息
Arch Ophthalmol. 2003 Feb;121(2):211-7. doi: 10.1001/archopht.121.2.211.
OBJECTIVES
To describe the vision-targeted, health-related quality of life, measured with the National Eye Institute Visual Function Questionnaire (NEI-VFQ), in patients with age-related macular degeneration, cataract, or reduced visual acuity; to determine the relationship between the NEI-VFQ subscale scores and clinical measures of visual function; and to assess the internal consistency and reliability of the NEI-VFQ subscales.
DESIGN
The 39-item NEI-VFQ was administered at the 5-year clinic visit to 4077 Age-Related Eye Disease Study participants.
RESULTS
The subscales of the NEI-VFQ had moderate to high internal consistency (Cronbach's alpha = 0.58-0.91). The NEI-VFQ scores for participants with advanced age-related macular degeneration in 1 or both eyes, severe nuclear opacity, reduced visual acuity, or cataract surgery generally were lower than scores for disease-free participants (P<.001).
CONCLUSION
These findings support the use of the NEI-VFQ as a measure of vision-targeted, health-related quality of life among patients with age-related macular degeneration, cataract, or reduced visual acuity.
目的
使用美国国立眼科研究所视觉功能问卷（NEI-VFQ）描述年龄相关性黄斑变性、白内障或视力下降患者以视力为导向的健康相关生活质量；确定NEI-VFQ分量表得分与视觉功能临床指标之间的关系；并评估NEI-VFQ分量表的内部一致性和可靠性。
设计
在为期5年的门诊随访中，对4077名年龄相关性眼病研究参与者进行了39项NEI-VFQ问卷调查。
结果
NEI-VFQ的分量表具有中度到高度的内部一致性（克朗巴赫α系数=0.58-0.91）。一只或两只眼睛患有晚期年龄相关性黄斑变性、严重核性混浊、视力下降或接受过白内障手术的参与者的NEI-VFQ得分通常低于无疾病参与者的得分（P<0.001）。
结论
这些发现支持将NEI-VFQ用作年龄相关性黄斑变性、白内障或视力下降患者以视力为导向的健康相关生活质量的衡量指标。
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