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用香肠诱饵中的疫苗对赤狐(赤狐属)进行狂犬病免疫接种。

Rabies immunization of red foxes (Vulpes fulva) with vaccine in sausage baits.

作者信息

Winkler W G, Baer G M

出版信息

Am J Epidemiol. 1976 Apr;103(4):408-15. doi: 10.1093/oxfordjournals.aje.a112240.

Abstract

Foxes were orally vaccinated against rabies with two modified live vaccine viruses, ERA/BHK-21 and PRI strain, in sausage baits. The baits proved acceptable to caged foxes and effectively delivered immunizing doses of vaccine. Antibody profiles on the vaccinated foxes and intramuscular challenge with "street" rabies virus showed the ERA/BHK-21 vaccine to be more effective than the PRI vaccine. The addition of a stabilizer helped maintain virus titers when the baits were subjected to high (35 C) temperature.

摘要

用两种狂犬病减毒活疫苗病毒ERA/BHK - 21和PRI株,在香肠诱饵中对狐狸进行口服狂犬病疫苗接种。这些诱饵被证明笼养狐狸可以接受,并能有效地提供免疫剂量的疫苗。对接种疫苗的狐狸的抗体谱以及用“街”狂犬病病毒进行肌肉内攻击试验表明,ERA/BHK - 21疫苗比PRI疫苗更有效。当诱饵置于高温(35摄氏度)环境时,添加稳定剂有助于维持病毒滴度。

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