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大麻工人的慢性呼吸道疾病。一项1967 - 1974年的随访研究。

Chronic respiratory disease in hemp workers. A follow-up study, 1967-1974.

作者信息

Bouhuys A, Zuskin E

出版信息

Ann Intern Med. 1976 Apr;84(4):398-405. doi: 10.7326/0003-4819-84-4-398.

Abstract

Many soft-hemp workers with more than 20 years' exposure to dust have chronic respiratory symptoms and obstructive lung function loss. During 7 years of follow-up, these workers had significantly higher occurrences of chronic cough and phlegm and dyspnea than control subjects and a significantly larger annual decline of forced expiratory volume in 1 second (FEV1.0) than control subjects, with a particularly marked difference between 20- to 44-year-old nonsmoking controls and hemp workers. We believe that deterioration of lung function among hemp workers begins before the age of 45 and that it continues even if further exposure to dust ceases. Textile workers should be advised to avoid further exposure to dust at a time when their ventilatory lung function (in the absence of effects of acute exposure) is sufficient to prevent future development of disabling function loss.

摘要

许多接触粉尘超过20年的软麻工人患有慢性呼吸道症状和阻塞性肺功能丧失。在7年的随访期间,这些工人慢性咳嗽、咳痰和呼吸困难的发生率显著高于对照组,且一秒用力呼气量(FEV1.0)的年下降幅度显著大于对照组,在20至44岁的非吸烟对照组和麻工之间差异尤为明显。我们认为,麻工的肺功能恶化在45岁之前就已开始,并且即使停止进一步接触粉尘仍会继续。应建议纺织工人在其通气肺功能(在无急性接触影响的情况下)足以预防未来出现致残性功能丧失时,避免进一步接触粉尘。

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