Zuskin E, Kanceljak B, Pokrajac D, Schachter E N, Witek T J
Andrija Stampar School of Public Health, Zagreb, Yugoslavia.
Br J Ind Med. 1990 Sep;47(9):627-32. doi: 10.1136/oem.47.9.627.
Respiratory symptoms and abnormalities of lung function were studied in 84 female and 27 male hemp workers employed in two textile mills (A and B) processing soft hemp (C sativa). In mill A 46 women and 27 men were investigated and 38 female workers were studied in mill B. Forty nine women and 30 men from a non-dusty industry served as controls. A significantly higher prevalence of almost all chronic respiratory symptoms was found in female hemp workers when compared to control workers. Among the men these differences were significant for nasal catarrh and sinusitis. A high prevalence of byssinosis was found among female hemp workers in both mills (group A, 47.8%; group B, 57.9%) as well as in the male workers (66.7%). Statistically significant across shift reductions in lung function were found for all ventilatory capacity measurements in female and male hemp workers varying from 7.1% for forced expiratory volume in one second (FEV1) to 15.1% for flow rates at 50% vital capacity (FEF50). Measured Monday baseline values before the work shift were significantly lower than expected for hemp workers, being particularly reduced for FEF25 and FEF50. The data suggest that occupational exposure to hemp dust is a significant risk factor for the development of acute and chronic lung disease in workers employed in this textile industry.
对两家加工软大麻（大麻）的纺织厂（A厂和B厂）的84名女性和27名男性大麻工人的呼吸道症状和肺功能异常进行了研究。在A厂，对46名女性和27名男性进行了调查，在B厂对38名女工进行了研究。来自非粉尘行业的49名女性和30名男性作为对照。与对照工人相比，女性大麻工人中几乎所有慢性呼吸道症状的患病率显著更高。在男性中，鼻粘膜炎和鼻窦炎的差异具有统计学意义。两个工厂的女性大麻工人（A组，47.8%；B组，57.9%）以及男性工人（66.7%）中棉尘肺的患病率都很高。在女性和男性大麻工人中，所有通气能力测量值在轮班期间的肺功能下降在统计学上都具有显著意义，从一秒用力呼气量（FEV1）的7.1%到肺活量50%时的流速（FEF50）的15.1%不等。工作日开始前测量的周一基线值显著低于大麻工人的预期值，FEF25和FEF50尤其降低。数据表明，职业接触大麻粉尘是该纺织行业工人发生急慢性肺病的一个重要风险因素。
