Kokubun Tetsuo, Veitch Nigel C, Bridge Paul D, Simmonds Monique S J
Royal Botanic Gardens, Kew, Richmond, Surrey, TW9 3AB, UK.
Phytochemistry. 2003 Mar;62(5):779-82. doi: 10.1016/s0031-9422(02)00606-4.
Two dihydroisocoumarins, 3,5-dimethyl-8-hydroxy-7-methoxy-3,4-dihydroisocoumarin and 3,5-dimethyl-8-methoxy-3,4-dihydroisocoumarin were isolated from a culture filtrate of Cytospora eucalypticola, together with three known dihydroisocoumarins and a tetralone derivative. Their structures were determined by spectroscopic methods. These isocoumarins are mildly antifungal, and antibacterial towards gram positive bacteria. A known compound, 5-hydroxymethylmellein, showed mild antifeedant activity towards Spodoptera littoralis.
从桉生孢壳菌的培养滤液中分离出两种二氢异香豆素,即3,5-二甲基-8-羟基-7-甲氧基-3,4-二氢异香豆素和3,5-二甲基-8-甲氧基-3,4-二氢异香豆素,同时还分离出三种已知的二氢异香豆素和一种四氢萘酮衍生物。它们的结构通过光谱方法确定。这些异香豆素具有轻度抗真菌活性,对革兰氏阳性菌有抗菌作用。一种已知化合物5-羟甲基蜜环菌素对棉铃虫表现出轻度拒食活性。