生活方式与白细胞计数之间的关联：一项针对日本男性上班族的研究。
Association between lifestyle and white blood cell count: a study of Japanese male office workers.
作者信息
Nakanishi Noriyuki, Suzuki Kenji, Tatara Kozo
机构信息
Department of Social and Environmental Medicine, Course of Social Medicine, Osaka University Graduate School of Medicine F2, 2-2 Yamada-oka, Suita-shi, Osaka 565-0871, Japan.
出版信息
Occup Med (Lond). 2003 Mar;53(2):135-7. doi: 10.1093/occmed/kqg029.
METHODS
We assessed the association of lifestyle factors with white blood cell (WBC) count in 3681 Japanese male office workers aged 35-59 years.
RESULTS
The WBC count differed significantly across lifestyle factors (overall obesity, alcohol consumption, cigarette smoking, eating breakfast, nutritional balance, physical exercise and hours of work). From multiple linear regression analyses, overall obesity, alcohol intake, cigarette smoking, nutritional balance and hours of work remained as statistically significant factors associated with WBC count. The WBC count increment showed a positive dose-response relationship with poor lifestyle factors regarding overall obesity, cigarette smoking and nutritional balance. On the other hand, the WBC count increment showed a negative dose-response relationship with alcohol intake and hours of work.
CONCLUSION
These data indicate that lifestyle factors may exert an important effect on WBC count.
方法
我们评估了3681名年龄在35至59岁的日本男性上班族的生活方式因素与白细胞（WBC）计数之间的关联。
结果
白细胞计数在不同生活方式因素（总体肥胖、饮酒、吸烟、吃早餐、营养平衡、体育锻炼和工作时长）之间存在显著差异。通过多元线性回归分析，总体肥胖、酒精摄入量、吸烟、营养平衡和工作时长仍然是与白细胞计数相关的统计学显著因素。白细胞计数的增加与总体肥胖、吸烟和营养平衡方面不良的生活方式因素呈正剂量反应关系。另一方面，白细胞计数的增加与酒精摄入量和工作时长呈负剂量反应关系。
结论
这些数据表明生活方式因素可能对白细胞计数产生重要影响。
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