Yang N Y, Macdonald I B, Desai I D, Lee M
Proc Soc Exp Biol Med. 1976 Apr;151(4):770-4. doi: 10.3181/00379727-151-39304.
Both excess dietary vitamin E and vitamin E deficiency in rats can significantly depress the activity of GSH peroxidase in liver and plasma of rats. Of all the six levels of vitamin E tested in this study, the dietary level of vitamin E found to maintain the maximum activity of GSH peroxidase in tissues of rats was somewhere between 25 and 250 IU/kg diet. This study conclusively indicates that the excess dietary vitamin E represses GSH peroxidase activity.
