Katerere David R, Gray Alexander I, Nash Robert J, Waigh Roger D
Department of Pharmaceutical Sciences, Strathclyde Institute for Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 ONR, Scotland, UK.
Phytochemistry. 2003 May;63(1):81-8. doi: 10.1016/s0031-9422(02)00726-4.
Four pentacyclic tritepenes were isolated from Combretum imberbe Engl. & Diels, of which two are novel glycosidic derivatives of 1alpha,3beta,23-trihydroxyolean-12-en-29-oic acid (hydroxyimberbic acid). Terminalia stuhlmannii Engl. & Diels stem bark yielded two glycosides of hydroxyimberbic acid, one of which is reported for the first time. The structures of the isolated compounds were elucidated by spectroscopic methods. Several of the compounds had antibacterial activity, imberbic acid showing particularly potent activity against Mycobacterium fortuitum and Staphylococcus aureus.
从南非风车子（Combretum imberbe Engl. & Diels）中分离出了四种五环三萜，其中两种是1α,3β,23-三羟基齐墩果-12-烯-29-酸（羟基南非风车子酸）的新型糖苷衍生物。非洲榄仁（Terminalia stuhlmannii Engl. & Diels）的茎皮产生了两种羟基南非风车子酸的糖苷，其中一种是首次报道。通过光谱方法阐明了分离出的化合物的结构。其中几种化合物具有抗菌活性，南非风车子酸对偶然分枝杆菌和金黄色葡萄球菌显示出特别强的活性。
