Epstein L, Miller G J, Stitt F W, Morris J N
Br Heart J. 1976 Apr;38(4):403-9. doi: 10.1136/hrt.38.4.403.
During 1968 to 1970, approximately 17 000 middle-aged male executive grade civil service officers, all of them engaged in sedentary or very light work, recorded on a Monday morning their leisure time activities over the previous Friday and Saturday. In 1971 a sample of 509 of these men completed further questionnaires for medical, social, and smoking history; these men had a resting electrocardiogram, and height, weight, skinfold thickness, blood pressure, and plasma total cholesterol were measured. Vigorous exercise in leisure time had previously been reported by 125 (25%) of the men, and these as a group had significantly fewer electrocardiographic abnormalities (changes compatible with myocardial ischaemia, ectopic beats, and sinus tachycardia) than the men not reporting vigorous exercise (P less than 0-02). This difference remained when all men with any history suggestive of cardiovascular disease were excluded from the analysis. Blood pressure, plasma total cholesterol, and smoking habits were examined with respect both to vigorous exercise and to the electrocardiogram, but the only relation found was that electrocardiographic abnormality increased with increasing blood pressure. Even among men with higher pressures, however, those reporting vigorous exercise had fewer electrographic abnormalities than the others. The results provide further support for the association of habitual physical activity with coronary health.
在1968年至1970年期间,约17000名中年男性行政级公务员,他们都从事久坐或极轻体力工作,于周一上午记录了上周五和周六的休闲活动。1971年,从这些人中抽取了509人作为样本,完成了关于医疗、社会和吸烟史的进一步问卷调查;这些人进行了静息心电图检查,并测量了身高、体重、皮褶厚度、血压和血浆总胆固醇。之前有125名(25%)男性报告在休闲时间有剧烈运动,与未报告有剧烈运动的男性相比,这组男性的心电图异常(与心肌缺血、异位搏动和窦性心动过速相符的变化)明显更少(P小于0.02)。当将所有有任何心血管疾病史的男性排除在分析之外时,这种差异仍然存在。对剧烈运动和心电图分别检查了血压、血浆总胆固醇和吸烟习惯,但唯一发现的关系是心电图异常随血压升高而增加。然而,即使在血压较高的男性中,报告有剧烈运动的男性的心电图异常也比其他人少。这些结果为习惯性体力活动与冠状动脉健康之间的关联提供了进一步的支持。