Tenniswood M, Bird C E, Clark A F
Can J Biochem. 1976 Apr;54(4):350-7. doi: 10.1139/o76-051.
Our investigations on acid phosphatase (AP) were aimed at finding a biochemical assay marker for androgen actions in the rat prostrate. We quantitatively examined the effects of l-tartrate or formaldehyde on AP activity in tissue filtrates from nine adult male rat tissues, plasma and hemolysed red blood cells (HRBC). There was significant inhibition of AP activity in all instances with the exception of HRBC with tartrate. The prostate inhibition results were not different from those for seminal vesicles and adrenals but were different from the other tissues studied. Ten days following castration the inhibition by tartrate was less in all tissues studied except plasma and HRBC; the formaldehyde inhibition percentages were not altered.
我们对酸性磷酸酶（AP）的研究旨在寻找一种大鼠前列腺中雄激素作用的生化检测标志物。我们定量检测了L-酒石酸盐或甲醛对来自九种成年雄性大鼠组织、血浆和溶血红细胞（HRBC）的组织滤液中AP活性的影响。除了酒石酸盐对HRBC的影响外，在所有情况下AP活性均受到显著抑制。前列腺的抑制结果与精囊和肾上腺的结果没有差异，但与其他研究组织不同。去势十天后，除血浆和HRBC外，酒石酸盐对所有研究组织的抑制作用均减弱；甲醛的抑制百分比没有改变。
