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黄色肉芽肿性胆囊炎伴肝脏和结肠广泛肿瘤样浸润,形似癌。

Xanthogranulomatous cholecystitis resembling carcinoma with extensive tumorous infiltration of the liver and colon.

作者信息

Pinocy Jürgen, Lange Antje, König Claudius, Kaiserling Edwin, Becker Horst D, Kröber Stefan M

机构信息

Department of Surgery, University of Tübingen, Liebermeisterstrasse 8, 72076 Tübingen, Germany.

出版信息

Langenbecks Arch Surg. 2003 Mar;388(1):48-51. doi: 10.1007/s00423-003-0362-x. Epub 2003 Mar 20.

DOI:10.1007/s00423-003-0362-x
PMID:12690480
Abstract

BACKGROUND

Xanthogranulomatous cholecystitis is a macrophage-rich inflammatory condition of the gallbladder that occasionally presents with tumorlike appearance.

CASE PRESENTATION

In the present case the inflammation involved all the layers of the gallbladder, the surrounding connective tissue, and part of the right lobe of the liver and right transverse colon. The clinical and radiological findings were suggestive of advanced carcinoma of the gallbladder. However, intraoperative frozen section investigation revealed xanthogranulomatous cholecystitis, for which simple cholecystectomy is the treatment of choice.

CONCLUSIONS

The original cause of the condition is unclear in most cases. In the present case it is possible that rupture of the gallbladder in association with the patient's known history of trauma have initiated the process.

摘要

背景

黄色肉芽肿性胆囊炎是一种富含巨噬细胞的胆囊炎症性疾病,偶尔表现出肿瘤样外观。

病例介绍

在本病例中,炎症累及胆囊全层、周围结缔组织以及肝右叶和右横结肠的一部分。临床和影像学检查结果提示为晚期胆囊癌。然而,术中冰冻切片检查显示为黄色肉芽肿性胆囊炎,对此单纯胆囊切除术是首选治疗方法。

结论

在大多数情况下,该病的病因尚不清楚。在本病例中,胆囊破裂可能与患者已知的创伤史有关,从而引发了这一过程。

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Langenbecks Arch Surg. 2003 Mar;388(1):48-51. doi: 10.1007/s00423-003-0362-x. Epub 2003 Mar 20.
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Cureus. 2025 Jan 29;17(1):e78205. doi: 10.7759/cureus.78205. eCollection 2025 Jan.
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Utility and diagnostic accuracy of intraoperative frozen sections in hepato-pancreato-biliary surgical pathology.术中冰冻切片在肝胰胆外科病理学中的应用及诊断准确性
Langenbecks Arch Surg. 2023 Oct 9;408(1):390. doi: 10.1007/s00423-023-03124-8.
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Xanthogranulomatous cholecystitis: diagnostic complexity and review of the literature.

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Imaging benign and malignant disease of the gallbladder.胆囊良恶性疾病的影像学表现
Radiol Clin North Am. 2002 Dec;40(6):1307-23, vi. doi: 10.1016/s0033-8389(02)00042-8.
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What should be done in patients diagnosed with xanthogranulomatous cholecystitis? Case-control study.对于被诊断为黄色肉芽肿性胆囊炎的患者应该采取什么措施?病例对照研究。
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Strategies for Differentiating Gallbladder Carcinoma from Xanthogranulomatous Cholecystitis-a Tertiary Care Centre Experience.鉴别胆囊癌与黄色肉芽肿性胆囊炎的策略——一家三级医疗中心的经验
Indian J Surg Oncol. 2017 Dec;8(4):554-559. doi: 10.1007/s13193-017-0677-7. Epub 2017 Jul 27.
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Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma: An analysis of 42 cases.酷似胆囊癌的黄色肉芽肿性胆囊炎:42例分析
World J Gastroenterol. 2015 Nov 28;21(44):12653-9. doi: 10.3748/wjg.v21.i44.12653.
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Xanthogranulomatous cholecystitis: Difficulty in differentiating from gallbladder cancer.黄色肉芽肿性胆囊炎:与胆囊癌鉴别困难。
World J Gastroenterol. 2015 Sep 21;21(35):10166-73. doi: 10.3748/wjg.v21.i35.10166.
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Xanthogranulomatous cholecystitis masquerading as gallbladder cancer: can it be diagnosed preoperatively?伪装成胆囊癌的黄色肉芽肿性胆囊炎:能否在术前诊断?
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Xanthogranulomatous cholecystits in 2-month-old infant.2个月大婴儿的黄色肉芽肿性胆囊炎
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