Weigl Josef A I, Bader Hans M, Everding Achim, Schmitt Heinz J
Paediatric Infectious Diseases, Children's Hospital University Kiel, Kiel, Germany.
Eur J Pediatr. 2003 May;162(5):309-16. doi: 10.1007/s00431-002-1140-4. Epub 2003 Mar 6.
Community-acquired pneumonia (CAP) is of predominant interest in analysing the burden of airway diseases. No population-based incidence data for children in Germany exist. In retrospective cohort studies from 1999 to 2001, parents of an entire age-class (28,000-30,000) of 5- to 7-year-old children at school entry medical examination (S1) in a complete federal state (Schleswig-Holstein, population 2.77 million) were interviewed by the Children and Adolescent Service of the Public Health Service. CAP was defined as pneumonia diagnosed by a physician at the time it occurred. The proportion of children investigated (participation rate) was 82.0-86.1%. The CAP-positive rate was 6.7-7.4%, 6.9-8.2% of whom had recurrent CAP. The mean age at first CAP was 36.4-39.4 months (median 42 months). This resulted in a population-based incidence for the age groups 0-1 year and 0-5 years (under 5) of 1,664-1,932 and 1,369-1,690 per 100,000, respectively; 93.7-95.9% received antibiotics. For each percent of CAP, 458 days (1999), 312 days (2000) and 319 days (2001) of at least one parent's work were lost, respectively.
Despite a relatively weak case definition, the population-based incidence of CAP before school entry was the same as recently reported form California and about 30-50% of that reported 20 to 40 years ago in the USA and Finland.
社区获得性肺炎(CAP)是分析气道疾病负担时主要关注的对象。德国尚无基于人群的儿童发病率数据。在1999年至2001年的回顾性队列研究中,石勒苏益格-荷尔斯泰因州(人口277万)的儿童与青少年公共卫生服务部门对一个完整联邦州内入学体检(S1)时的一整个年龄段(28000 - 30000名)5至7岁儿童的家长进行了访谈。CAP定义为发病时由医生诊断的肺炎。接受调查的儿童比例(参与率)为82.0% - 86.1%。CAP阳性率为6.7% - 7.4%,其中6.9% - 8.2%为复发性CAP。首次发生CAP的平均年龄为36.4 - 39.4个月(中位数42个月)。这导致0至1岁和0至5岁(5岁以下)年龄组的基于人群的发病率分别为每10万人1664 - 1932例和1369 - 1690例;93.7% - 95.9%的患儿接受了抗生素治疗。每发生1%的CAP,至少一位家长分别损失了458天(1999年)、312天(2000年)和319天(2001年)的工作时间。
尽管病例定义相对宽松,但入学前CAP的基于人群的发病率与最近加利福尼亚州报告的相同,约为20至40年前美国和芬兰报告发病率的30% - 50%。