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灵长类动物小脑动眼蚓部损伤对眼球运动的影响:双眼控制

Effects of lesions of the cerebellar oculomotor vermis on eye movements in primate: binocular control.

作者信息

Takagi Mineo, Tamargo Rafael, Zee David S

机构信息

Divisions of Ophthalmology and Visual Science, Niigata University, Graduate School of Medical and Dental Sciences, CREST, Japan Science and Technology, Niigata, 951-8510, Japan.

出版信息

Prog Brain Res. 2003;142:19-33. doi: 10.1016/S0079-6123(03)42004-9.

DOI:10.1016/S0079-6123(03)42004-9
PMID:12693252
Abstract

The effects of lesions of the dorsal 'oculomotor' cerebellar vermis on binocular oculomotor functions in three monkeys were examined. Prominent findings included (1) a convergence bias during monocular fixation, i.e., an 'esodeviation' in the absence of disparity cues, (2) a loss of comitancy, i.e., alignment varies more with orbital position, (3) abnormal saccade yoking producing saccade disconjugacy, and (4) defects in prism-induced phoria adaptation. There was also a suggestion of a disturbance in the dynamic properties of disparity-induced vergence. These findings point to a role for the 'oculomotor' vermis in binocular aspects of the control of eye movements.

摘要

研究了三只猴子背侧“动眼神经”小脑蚓部损伤对双眼动眼功能的影响。主要发现包括:(1)单眼注视时存在集合偏差,即在无视差线索时出现“内斜视”;(2)一致性丧失,即眼球位置随眼眶位置变化更大;(3)异常的扫视联带运动导致扫视非共轭;(4)棱镜诱导性隐斜适应缺陷。此外,还有证据表明视差诱导性辐辏的动态特性受到干扰。这些发现表明“动眼神经”蚓部在眼球运动控制的双眼方面发挥作用。

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