肾细胞癌胰腺转移灶非典型切除术后复发率高。
High recurrence rate after atypical resection for pancreatic metastases from renal cell carcinoma.
作者信息
Bassi C, Butturini G, Falconi M, Sargenti M, Mantovani W, Pederzoli P
机构信息
Pancreatic Unit, Department of Surgical and Gastroenterological Sciences, Policlinico B. Roma, Verona University, Verona, Italy.
出版信息
Br J Surg. 2003 May;90(5):555-9. doi: 10.1002/bjs.4072.
BACKGROUND
Pancreatic metastases from renal cell carcinoma are rare but highly resectable. The aim of this study was to review a series of patients with this condition.
METHODS
The study involved 22 consecutive patients with histologically proven pancreatic metastases from renal cell cancer.
RESULTS
Seventeen of the 22 patients had surgery. No patient died but eight of the 17 patients had a postoperative complication. Median follow-up was 33 (range 1-96) months. The 24- and 60-month survival probabilities were 0.84 and 0.53 respectively. Five patients who did not undergo surgery had 24- and 60-month survival probabilities of 0.53 and 0.26 respectively. The difference between the two groups was significant (P = 0.040).
CONCLUSION
Despite the slow development of these secondaries and their well encapsulated morphology, the high rate of recurrence after limited resection suggests that radical resection should be recommended.
背景
肾细胞癌的胰腺转移罕见，但大多可切除。本研究旨在回顾一系列患有这种疾病的患者。
方法
本研究纳入了22例经组织学证实为肾细胞癌胰腺转移的连续患者。
结果
22例患者中有17例接受了手术。无患者死亡，但17例患者中有8例出现术后并发症。中位随访时间为33（范围1 - 96）个月。24个月和60个月的生存概率分别为0.84和0.53。5例未接受手术的患者24个月和60个月的生存概率分别为0.53和0.26。两组之间的差异具有统计学意义（P = 0.040）。
结论
尽管这些转移灶发展缓慢且形态包膜完整，但有限切除后的高复发率表明应推荐根治性切除。
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