Walker Bailus, Stokes Lynette D, Warren Rueben
Howard University Medical Center, Environmental Health Administration, District of Columbia Department of Health, Washington, USA.
J Natl Med Assoc. 2003 Feb;95(2):152-66.
Asthma, a disease of attacks and remission, continues to account for substantial morbidity and direct economic costs. Numerous studies--epidemiologic, toxicologic and clinical--present evidence for a broad spectrum of environmental risk factors associated with asthma. This review summarizes current thinking on a subset of these factors. Knowledge of potential environmental determinants of asthma is important to both the patient and healthcare professional in the application of multiple modalities of medical and environmental intervention for management of the development, and exacerbation of this chronic inflammatory disorder of the airways.
哮喘是一种发作与缓解交替出现的疾病,仍造成大量发病情况和直接经济成本。众多研究——流行病学、毒理学及临床研究——都提供了与哮喘相关的广泛环境风险因素的证据。本综述总结了对这些因素中一部分因素的当前认识。了解哮喘潜在的环境决定因素,对于患者和医护人员在应用多种医学和环境干预方式来管理这种气道慢性炎症性疾病的发生和加重方面都很重要。