Wu S, Bach F H, Auerbach R
J Exp Med. 1975 Nov 1;142(5):1301-5. doi: 10.1084/jem.142.5.1301.
While spleen cells from neonatal B10 (H-2b) are reactive (proliferate) in one-way mixed leukocyte culture, cell-mediated lympholysis reactivity does not arise until 7 days of age. When B10 cells are sensitized to B10.D2 (H-2d), cross-killing of third-party B10.BR (H-2k) target is always lower than the specific killing of B10.D2 targets and is not demonstrable until 27 days after birth.
虽然新生B10(H-2b)的脾细胞在单向混合淋巴细胞培养中具有反应性(增殖),但细胞介导的淋巴细胞溶解反应性直到7日龄才出现。当B10细胞对B10.D2(H-2d)致敏时,对第三方B10.BR(H-2k)靶细胞的交叉杀伤总是低于对B10.D2靶细胞的特异性杀伤,并且直到出生后27天才可检测到。