细胞介导的免疫：混合淋巴细胞反应和细胞介导的淋巴细胞溶解的差异成熟
Cell-mediated immunity: differential maturation of mixed leukocyte reaction and cell-mediated lympholysis.
作者信息
Wu S, Bach F H, Auerbach R
出版信息
J Exp Med. 1975 Nov 1;142(5):1301-5. doi: 10.1084/jem.142.5.1301.
Abstract
While spleen cells from neonatal B10 (H-2b) are reactive (proliferate) in one-way mixed leukocyte culture, cell-mediated lympholysis reactivity does not arise until 7 days of age. When B10 cells are sensitized to B10.D2 (H-2d), cross-killing of third-party B10.BR (H-2k) target is always lower than the specific killing of B10.D2 targets and is not demonstrable until 27 days after birth.
摘要
虽然新生B10（H-2b）的脾细胞在单向混合淋巴细胞培养中具有反应性（增殖），但细胞介导的淋巴细胞溶解反应性直到7日龄才出现。当B10细胞对B10.D2（H-2d）致敏时，对第三方B10.BR（H-2k）靶细胞的交叉杀伤总是低于对B10.D2靶细胞的特异性杀伤，并且直到出生后27天才可检测到。
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