Antonsson Annika, Erfurt Cornelia, Hazard Kristina, Holmgren Veroniqa, Simon Melinda, Kataoka Akio, Hossain Shahadat, Håkangård Camilla, Hansson Bengt Göran
Department of Medical Microbiology, Malmö University Hospital, Lund University, SE-20502 Malmö, Sweden.
Department of Oncology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.
J Gen Virol. 2003 Jul;84(Pt 7):1881-1886. doi: 10.1099/vir.0.18836-0.
In order to investigate whether previous findings of ubiquitous skin papillomavirus infection in Caucasians apply to populations from other parts of the world, skin swab samples from Bangladesh, Japan, Ethiopia and Zambia were analysed in parallel with Swedish samples. The prevalence of HPV DNA in the material from Bangladesh was 68 %, Japan 54 %, Ethiopia 52 %, Zambia 42 % and Sweden 70 %. A great multiplicity of genotypes was demonstrated by the finding of 88 HPV types or putative types in 142 HPV DNA-positive samples in total. Double or multiple genotypes were frequently found in the same sample. The most prevalent HPV type was HPV-5, with an overall prevalence of 6.5 %. This was also the only type that was found in samples from all of the countries in the study. The results presented show that commensal skin HPV infections have a worldwide distribution with a very broad spectrum of genotypes.
为了研究先前关于高加索人普遍存在皮肤乳头瘤病毒感染的研究结果是否适用于世界其他地区的人群，对来自孟加拉国、日本、埃塞俄比亚和赞比亚的皮肤拭子样本与瑞典样本进行了平行分析。孟加拉国样本中HPV DNA的患病率为68%，日本为54%，埃塞俄比亚为52%，赞比亚为42%，瑞典为70%。在总共142个HPV DNA阳性样本中发现了88种HPV类型或推定类型，证明了基因型的高度多样性。在同一样本中经常发现双重或多重基因型。最常见的HPV类型是HPV-5，总体患病率为6.5%。这也是在该研究所有国家的样本中都发现的唯一类型。所呈现的结果表明，共生皮肤HPV感染在全球范围内分布，基因型范围非常广泛。
