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脑膜炎球菌性脑膜炎和败血症的病理生理学

Pathophysiology of meningococcal meningitis and septicaemia.

作者信息

Pathan N, Faust S N, Levin M

机构信息

Imperial College of Science, Technology & Medicine, London, UK.

出版信息

Arch Dis Child. 2003 Jul;88(7):601-7. doi: 10.1136/adc.88.7.601.

Abstract

Neisseria meningitidis is remarkable for the diversity of interactions that the bacterium has with the human host, ranging from asymptomatic nasopharyngeal colonisation affecting virtually all members of the population; through focal infections of the meninges, joints, or eye; to the devastating and often fatal syndrome of meningococcal septic shock and purpura fulminans.

摘要

脑膜炎奈瑟菌与人类宿主的相互作用具有多样性,这一点十分显著。其相互作用范围广泛,从几乎影响所有人群的无症状鼻咽部定植,到脑膜、关节或眼部的局部感染,再到脑膜炎球菌性败血症休克和暴发性紫癜这种极具破坏性且往往致命的综合征。

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