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Motif3D:将蛋白质序列基序与三维结构相关联。

Motif3D: Relating protein sequence motifs to 3D structure.

作者信息

Gaulton Anna, Attwood Teresa K

机构信息

School of Biological Sciences and Department of Computer Science, University of Manchester, Manchester M13 9PT, UK.

出版信息

Nucleic Acids Res. 2003 Jul 1;31(13):3333-6. doi: 10.1093/nar/gkg534.

Abstract

Motif3D is a web-based protein structure viewer designed to allow sequence motifs, and in particular those contained in the fingerprints of the PRINTS database, to be visualised on three-dimensional (3D) structures. Additional functionality is provided for the rhodopsin-like G protein-coupled receptors, enabling fingerprint motifs of any of the receptors in this family to be mapped onto the single structure available, that of bovine rhodopsin. Motif3D can be used via the web interface available at: http://www.bioinf.man.ac.uk/dbbrowser/motif3d/motif3d.html.

摘要

Motif3D是一个基于网络的蛋白质结构查看器,旨在使序列基序,特别是PRINTS数据库指纹中包含的那些基序,能够在三维(3D)结构上可视化。它还为视紫红质样G蛋白偶联受体提供了额外的功能,使该家族中任何一种受体的指纹基序都能映射到现有的单一结构上,即牛视紫红质的结构。可通过以下网络界面使用Motif3D:http://www.bioinf.man.ac.uk/dbbrowser/motif3d/motif3d.html。

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