Tanaka Takashi, Fukumori Masatake, Ochi Tomoko, Kouno Isao
Department of Molecular Medicinal Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
J Nat Prod. 2003 Jun;66(6):759-63. doi: 10.1021/np020608g.
Four new dimeric ellagitannins, paeonianins A-D (2-5), were isolated from the fruits of Paeonia lactiflora, together with a new ellagitannin monomer, paeonianin E (1). Their structures were determined by spectroscopic methods. Paeonianins A-D (2-5) are positional isomers formed by condensation of pentagalloyl-beta-D-glucose (8) with 5-desgalloylstachyurin (6) or casuariin (7). Paeonianin E is a C-glycosidic ellagitannin having a gallic acid methyl ester moiety at the glucose C-1 position. This is the first report of the isolation of dimeric ellagitannins from a plant in the family Paeoniaceae.
从芍药果实中分离出4种新的二聚鞣花单宁，即芍药苷A-D（2-5），以及一种新的鞣花单宁单体，芍药苷E（1）。通过光谱方法确定了它们的结构。芍药苷A-D（2-5）是由五倍没食子酰基-β-D-葡萄糖（8）与5-去没食子酰基原花青素（6）或澳洲栗木鞣花素（7）缩合形成的位置异构体。芍药苷E是一种C-糖苷鞣花单宁，在葡萄糖C-1位具有没食子酸甲酯部分。这是首次从芍药科植物中分离出二聚鞣花单宁的报道。
